Normal Amsler Grid appearance.
Appearance of Amsler grid with macular disease.
Note distorted image.
Appearance of Amsler grid with wet AMD.
Note distortion and darkened spot.
Age-related macular degeneration (AMD) is the most common cause of vision loss in persons over 50 years of age world-wide. Millions are affected, and because it is an aging change, AMD is becoming increasingly common as the world population ages.
“Dry” AMD is the earliest stage, and affects everyone with AMD. Most people with dry AMD have good vision on the eye chart, but have increasing difficulty at night and indoors, needing more light and higher contrast (black and white rather than shades of grey) to see well. Severe visual loss with dry AMD is uncommon, and usually occurs when a condition called “geographic atrophy” develops.
“The other day I realized that I was reading the scores at the bottom of the TV screen again. I couldn’t do that before the laser treatment. And the distortion and waviness was gone.” 76 year old woman with dry AMD.
“Wet” AMD is the most common reason people with dry AMD lose vision. This happens when an eye with dry AMD develops scar tissue growth under the center of the retina (called the macula), causing damage that destroys the macula and central, sharp vision. Without macular vision, your ability to read, recognize faces, and drive may be lost.
Retinal Protective Therapy™ (RPT™)
The first effective preventive treatment for AMD
Retinal Protective Therapy™ (RPT™) can reduce your risk of developing “wet” AMD. The Age-Related Eye Disease Study (AREDS) showed that vitamins can reduce the risk of visual loss in dry AMD by about 4% per year. Recent studies suggest that RPT can reduce your risk of developing wet AMD by over 90% per year even if you take AREDS vitamins. That is 22.5 times more effective than AREDS vitamins alone! At the same time, RPT™ improves indoor vision, making it easier to read and watch TV.
Most people with dry AMD keep good vision unless they develop wet AMD. However, some with dry AMD experience rapid and severe loss of central vision due to “wearing out” of the macula, called “geographic atrophy” (GA). Until recently, there has been no treatment for GA. However, RPT can reduce the rate of GA progression by over 50% per year compared to AREDS vitamins alone. RPT does this safely, while also improving indoor vision and reducing the risk of developing wet AMD. SDM RPT™ is the first treatment to safely slow progression of AMD, even in the most severe form of dry AMD – geographic atrophy.
If you have “wet” AMD, RPT™ can help in several important ways. As you know, drugs injected into the eye are the primary treatment for wet AMD. RPT™ helps these drugs work better. What does this mean? Injections can be significantly reduced without sacrificing visual results. By decreasing the number of injections, RPT can reduce the risks of vision-threatening complications of injections, such as macular atrophy, infection and glaucoma.
Real World Data. High Quality Data. An in-depth analysis of SDM RPT™ for AMD, using a national database of over 300 US retina specialists and over 300,000 AMD patients (Vestrum Health) throughout the US was done, to compare patients who did, or did not, receive SDM RPT™ treatment for AMD. Using a statistical method called “propensity scoring” to obtain the highest quality patient and risk-factor matching, SDM RPT™ was found to markedly reduce the development of wet AMD compared to standard care without SDM. Eyes with dry AMD receiving SDM RPT™ were 8.5 times less likely to develop wet AMD and need eye injections compared to AREDS vitamins alone (see graph below). In eyes with wet AMD, SDM RPT™ reduced the need eye injections by 67% compared to standard care without SDM, with the same visual results.
The Bottom Line: SDM RPT™ is the first and only treatment for AMD to provide each and every one of these critical sight-saving benefits:
Reduce the risk of developing wet AMD
Slow progression of geographic atrophy and dry AMD
Reduce the need for eye injections in wet AMD
Reduce the risk of vision loss from all causes in AMD
There is no drug or any other treatment that can do any of these things, let alone all of these things; and SDM RPT™ does them extraordinarily well. So well, in fact, that it will be very difficult for any future treatment to ever be as safe and effective as SDM RPT™ is, right now.
Studies have shown that the effects of RPT™ in AMD tend to wear off and return to pre-treatment levels about 6-9 months after treatment. Therefore, to maintain maximum treatment benefits to minimize your risks of vision loss from AMD, patients with AMD should repeat RPT™ every 3-4 months.